The Translational Genomics Hub (TGH) is a critical research platform within the Women and Children’s Health Research Institute (WCHRI) that accelerates the discovery of genetic causes for undiagnosed diseases in children. For pediatric clinical trials, the TGH is essential because identifying a causative gene is often the first step toward developing a novel, targeted treatment. The TGH removes key barriers for clinical investigators by managing complex logistics, including:
- Ethics and enrollment: Handling ethical requirements and much of the participant enrollment process.
- Sample management: Coordinating sample collection, tracking and logistics.
- Scientific access: Facilitating connections to specialized local scientists and potential research funding.
This streamlined support enables clinicians to apply cutting-edge research approaches to their patients, helping to pinpoint the genetic variants responsible for disease and fast-track the path from gene discovery to novel treatment development. TGH is supported through infrastructure and equipment located in the Stollery Children’s Hospital Foundation Innovation Laboratories.