The IGAR program incorporates one of the world’s first MR guided Linac systems, a very-high field (3T) whole body MR Imaging and Spectroscopy System for human studies, an animal 9.4T MR Imaging and Spectroscopy System, an image-fusion laboratory, and the computer laboratories. The MR systems provide the anatomical, functional, metabolic and biochemical information to identify diseases at an earlier stage, and monitor treatment response immediately after and at intervals after treatment. The resultant information is integrated with PET images within our image fusion laboratories to design advanced adaptive radiation therapy delivered by the experimental TomoTherapy system.